In August of 2003, one of the most important events regarding human health took place when researchers from Harvard Medical School and BIOMOL Research Laboratories discovered that resveratrol, an anti-oxidant found in red wine, activates a “longevity gene”. Once activated, this longevity gene, SIRT1, can extend an organisms life by up to 70% by repairing and duplicating DNA.
The results of their research and findings have led to resveratrol being regarded as the biggest medical breakthrough ever discovered because of its ability to inhibit and delay a wide number of illnesses including, but not limited to, cardiovascular disease, cancer, Type II Diabetes and depression.
BIOMOL Laboratories tested a sample of Revers♥e-vineTM at 10% concentration for SIRT 1 activation properties. The ingredient Revers♥e-vineTM is manufactured by Certified Nutraceuticals; a Murrieta, California based nutraceutical company has a proprietary extraction process. The Revers♥e-vineTM testing was done in two phases and the testing demonstrated the ability of Revers♥e-vineTM in stimulating SIRT1 activity.
In addition to SIRT 1 activation by resveratrol, the “Revers♥e-vineTM” ingredient exhibited another SIRT 1 activator, thought to be from trans-e-viniferin. Trans-e-viniferin is found in the cane, vine and stems of the grape and is believed to have equal or greater medical benefits than that of resveratrol…
Although trans-e-viniferin has not been studied as widely as trans-resveratrol, there is increasing evidence of the necessity of trans-e-viniferin in conjunction with trans-resveratrol for full absorption by the body. There is also scientific evidence that trans-e-viniferin amplifies the physiological effect of resveratrol.
In addition to being necessary for the full functionality of trans-resveratrol, trans-e-viniferin has been shown to have inhibit and disable tumor growth by inducing cancer cell death While trans-resveratrol is found primarily in the grape skin, trans-e-viniferin are found in the cane and vine of the grape.
Revers♥e-vineTM is the only supplement on the market today to contain trans-resveratrol, trans-e-viniferin, and oligostilbenes. Revers♥e-vineTM utilizes a proprietary extraction from a blend of grapevine, stem, red wine, and red grapes skin to obtain optimal bioavailability for the body
For additional information please visit www.certifiednutra.com or call (951) 600-3899
References:
Billiard, C.; Izard, J.C.; Roman, V.; Kern, C.; Mathiot, C.; Mentz, F.; Kolb, J.P. Comparative antiproliferative and apoptotic effects of resveratrol, e-viniferin and vine shots derived polyphenols (vineatrols) on chronic B lymphocytic leukemia cells and normal human lymphocytes. Leuk. Lymphoma. 2002, 43, 1991-2002. Howitz, K.; Bitterman, K.; Cohen, Haim.; Lamming, D.; Lavu, S.; Wood, J.; Zipkin, R.; Chung, P.; Kisielewski, A.; Zhang, L.; Scherer, B.; Sinclair, D. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature, Advance Online Publication. 2003, 1-5. Oshima,Y.; Namao, K.; Kamijou,A., Matsuoka, S.; Nakano, M.; Terao, K.; Ohizumi, Y. Powerful hepatoprotective and hepatotoxic plant oligostilbenes, isolated from the Oriental medicinal plant Vitis coignetiae (Vitaceae). Experientia. 1995, 52,63-66. Pussa, T.; Floren, J.; Kuldkepp, P.; Raal, A. Survey of Grapevine Vitis vinifera Stem Polyphenols by Liquid Chromatography-Diode Array Detection-Tandem Mass Spectrometry. J. Agric. Food Chem. 2006, 54, 7488-7494. Privat, C.; Telo, J.; Bernardes-Genisson, V; Vieira, A.; Souchard, J.; Nepveu, F.; Antioxidant Properties of trans-e-Viniferin as Compared to Stilbene Derivatives in Aqueous and Nonaqueous Media. J. Agric. Food Chem. 2002, 50, 1214-1217.